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- Bc82b0df464fe3ad35f652ff83c2fefac NCIT_P378 "NCI" @default.
- Bc82b0df464fe3ad35f652ff83c2fefac type Axiom @default.
- Bc82b0df464fe3ad35f652ff83c2fefac annotatedProperty IAO_0000115 @default.
- Bc82b0df464fe3ad35f652ff83c2fefac annotatedSource NCIT_C66277 @default.
- Bc82b0df464fe3ad35f652ff83c2fefac annotatedTarget "The hydrochloride salt form of oxprenolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-arrhythmic, anti-anginal and antihypertensive activities. Oxprenolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, oxprenolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels." @default.