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- Bc901a3845963cf29905c4543f6209828 NCIT_P378 "NCI" @default.
- Bc901a3845963cf29905c4543f6209828 type Axiom @default.
- Bc901a3845963cf29905c4543f6209828 annotatedProperty IAO_0000115 @default.
- Bc901a3845963cf29905c4543f6209828 annotatedSource NCIT_C48812 @default.
- Bc901a3845963cf29905c4543f6209828 annotatedTarget "A novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase." @default.