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- Bcb15720f092f61141e6416bd3101aeae NCIT_P378 "KEGG" @default.
- Bcb15720f092f61141e6416bd3101aeae type Axiom @default.
- Bcb15720f092f61141e6416bd3101aeae annotatedProperty NCIT_P325 @default.
- Bcb15720f092f61141e6416bd3101aeae annotatedSource NCIT_C38780 @default.
- Bcb15720f092f61141e6416bd3101aeae annotatedTarget "Natural products containing carbon-phosphorous bonds, so-called C-P compounds, are derivatives of phosphonate and phosphinate with substitution of alkyl group for hydrogen of phosphorus-hydrogen bonds. C-P compounds have been found in many organisms, but only protists and bacteria, mostly Actinobacteria, have biosynthetic capacity. A common reaction in the biosynthetic pathway is C-P bond forming reaction from phosphoenolpyruvate (PEP) to phosphonopyruvate (PnPy) catalyzed by PEP phosphomutase. 2-Aminoethylphosphonate (AEP) is the most abundant C-P compound in the natural world. AEP derivatives include phosphonoprotein, phosphonoglycan, and phosphonolipid. Other known C-P compounds are bioactive substances used in medicine (antibiotics) and agriculture (herbicide) such as fosfomycin, FR-33289, rhizocticin, and bialaphos." @default.