Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bcb1a547e584b30d92d98c1f5fbdd9d1b> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bcb1a547e584b30d92d98c1f5fbdd9d1b NCIT_P378 "NCI" @default.
- Bcb1a547e584b30d92d98c1f5fbdd9d1b type Axiom @default.
- Bcb1a547e584b30d92d98c1f5fbdd9d1b annotatedProperty IAO_0000115 @default.
- Bcb1a547e584b30d92d98c1f5fbdd9d1b annotatedSource NCIT_C118670 @default.
- Bcb1a547e584b30d92d98c1f5fbdd9d1b annotatedTarget "A liposome-based preparation consisting of the beta- and gamma-emitting radionuclide rhenium Re 188 (Re 188) linked to the chelator N,N-bis (2-mercaptoethyl)-N',N'-diethylethylenediamine (BMEDA) and encapsulated in liposomes, with potential tumor imaging and antineoplastic activities. Upon intravenous infusion of rhenium Re 188 BMEDA-labeled liposomes, the liposomes selectively target tumor cells, facilitate the retention of the radioisotope by those cells, and cause localized antitumor radiocytotoxicity while sparing surrounding normal, healthy cells. In addition, Re 188 BMEDA-labeled liposomes can be used for imaging purposes. Re 188 has a short half-life and a short path length, which further contribute to limiting the radiotoxicity to the tumor cells." @default.