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- Bcb3135562bc9f2091bcd7562d33bf89c NCIT_P378 "NCI" @default.
- Bcb3135562bc9f2091bcd7562d33bf89c type Axiom @default.
- Bcb3135562bc9f2091bcd7562d33bf89c annotatedProperty IAO_0000115 @default.
- Bcb3135562bc9f2091bcd7562d33bf89c annotatedSource NCIT_C179639 @default.
- Bcb3135562bc9f2091bcd7562d33bf89c annotatedTarget "A formulation consisting of lipid nanoparticles (LNPs) encapsulating nucleoside-modified messenger RNA (mRNA) encoding the endogenous cytokine interleukin-7 (IL-7), with potential immunostimulating activity. Upon administration, ribocytokine IL-7 BNT152 is taken up by cells and the expressed IL-7 targets and binds to the IL-7 receptor (IL7R). The binding of IL-7 to IL7R activates IL7/IL7R-mediated signaling, which activates B- and T- lymphocytes, may improve immune recovery and activation, and may enhance anti-tumor immune responses." @default.