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- Bcc35a1932df5cb64a0bbfc6759cac626 NCIT_P378 "NCI" @default.
- Bcc35a1932df5cb64a0bbfc6759cac626 type Axiom @default.
- Bcc35a1932df5cb64a0bbfc6759cac626 annotatedProperty IAO_0000115 @default.
- Bcc35a1932df5cb64a0bbfc6759cac626 annotatedSource NCIT_C1880 @default.
- Bcc35a1932df5cb64a0bbfc6759cac626 annotatedTarget "The hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Canertinib binds to the intracellular domains of epidermal growth factor receptor tyrosine kinases (ErbB family), irreversibly inhibiting their signal transduction functions and resulting in tumor cell apoptosis and suppression of tumor cell proliferation. This agent also acts as a radiosensitizing agent and displays synergistic activity with other chemotherapeutic agents." @default.