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- Bcc56cfd9ac73662e15d9357658a2d35c NCIT_P378 "NCI" @default.
- Bcc56cfd9ac73662e15d9357658a2d35c type Axiom @default.
- Bcc56cfd9ac73662e15d9357658a2d35c annotatedProperty IAO_0000115 @default.
- Bcc56cfd9ac73662e15d9357658a2d35c annotatedSource NCIT_C80089 @default.
- Bcc56cfd9ac73662e15d9357658a2d35c annotatedTarget "A synthetic 9-amino-anthracycline with antineoplastic activity. Amrubicin intercalates into DNA and inhibits the activity of topoisomerase II, resulting in inhibition of DNA replication, and RNA and protein synthesis, followed by cell growth inhibition and cell death. This agent has demonstrated a higher level of anti-tumor activity than conventional anthracycline drugs without exhibiting any indication of the cumulative cardiac toxicity common to this class of compounds." @default.