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- Bd0d1cde65ad18f7aec7823f50e59d5e2 NCIT_P378 "NCI" @default.
- Bd0d1cde65ad18f7aec7823f50e59d5e2 type Axiom @default.
- Bd0d1cde65ad18f7aec7823f50e59d5e2 annotatedProperty IAO_0000115 @default.
- Bd0d1cde65ad18f7aec7823f50e59d5e2 annotatedSource NCIT_C146821 @default.
- Bd0d1cde65ad18f7aec7823f50e59d5e2 annotatedTarget "A topical ointment composed of the water-insoluble taxane paclitaxel that has been processed to form uncoated nanoparticles, with potential antineoplastic activity. Upon topical administration of nanoparticle paclitaxel ointment SOR007 to the affected area, and following epithelial and dermal penetration, paclitaxel binds to tubulin and inhibits the disassembly of microtubules, which leads to the inhibition of cell division, thereby halting the proliferation of rapidly-dividing tumor cells. The nanoparticles in the nanoparticle paclitaxel ointment are produced through a specific proprietary submicron particle production." @default.