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- Bd0f7000e8d3b4a1e154b224854901c03 NCIT_P378 "NCI" @default.
- Bd0f7000e8d3b4a1e154b224854901c03 type Axiom @default.
- Bd0f7000e8d3b4a1e154b224854901c03 annotatedProperty IAO_0000115 @default.
- Bd0f7000e8d3b4a1e154b224854901c03 annotatedSource NCIT_C47560 @default.
- Bd0f7000e8d3b4a1e154b224854901c03 annotatedTarget "The pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine pamoate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine pamoate crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05)" @default.