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- Bd29f4e3230c4bd1640ab9e595ec8ce16 NCIT_P378 "NCI" @default.
- Bd29f4e3230c4bd1640ab9e595ec8ce16 type Axiom @default.
- Bd29f4e3230c4bd1640ab9e595ec8ce16 annotatedProperty IAO_0000115 @default.
- Bd29f4e3230c4bd1640ab9e595ec8ce16 annotatedSource NCIT_C2516 @default.
- Bd29f4e3230c4bd1640ab9e595ec8ce16 annotatedTarget "An antineoplastic antibiotic that is structurally similar to the benzoquinone ansamycin antibiotic geldanamycin. A geldanamycin analogue binds to HSP90, a chaperone protein that aids in the assembly, maturation, and folding of proteins. Subsequently, the function of HSP90 is inhibited, leading to the degradation and depletion of client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction." @default.