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- Bd5031383bc003d0cfdf6d77f20b7ae01 NCIT_P378 "NCI" @default.
- Bd5031383bc003d0cfdf6d77f20b7ae01 type Axiom @default.
- Bd5031383bc003d0cfdf6d77f20b7ae01 annotatedProperty IAO_0000115 @default.
- Bd5031383bc003d0cfdf6d77f20b7ae01 annotatedSource NCIT_C65974 @default.
- Bd5031383bc003d0cfdf6d77f20b7ae01 annotatedTarget "A beta-adrenergic receptor agonist with bronchodilator activity. Isoetharine selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells." @default.