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- Bd529e46181893b3fb148bcfd522a1ee4 NCIT_P378 "NCI" @default.
- Bd529e46181893b3fb148bcfd522a1ee4 type Axiom @default.
- Bd529e46181893b3fb148bcfd522a1ee4 annotatedProperty IAO_0000115 @default.
- Bd529e46181893b3fb148bcfd522a1ee4 annotatedSource NCIT_C1374 @default.
- Bd529e46181893b3fb148bcfd522a1ee4 annotatedTarget "A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in a depot formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function. (NCI04)" @default.