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- Bd54b8569a7fc4028f3f4e40b830300c8 NCIT_P378 "NCI" @default.
- Bd54b8569a7fc4028f3f4e40b830300c8 type Axiom @default.
- Bd54b8569a7fc4028f3f4e40b830300c8 annotatedProperty IAO_0000115 @default.
- Bd54b8569a7fc4028f3f4e40b830300c8 annotatedSource NCIT_C152073 @default.
- Bd54b8569a7fc4028f3f4e40b830300c8 annotatedTarget "A toxic metabolite derived from dietary proteins and tryptophan. In the intestine, proteins and tryptophan are converted to indole by tryptophanase-expressing organisms. In the liver, indole is hydroxylated to form indoxyl and indoxyl is sufated to produce indican. Overproduction of indican is associated with glomerular sclerosis, interstitial fibrosis and renal failure." @default.