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- Bd60b39f97feef479dee1a35a59717c1a NCIT_P378 "NCI" @default.
- Bd60b39f97feef479dee1a35a59717c1a type Axiom @default.
- Bd60b39f97feef479dee1a35a59717c1a annotatedProperty IAO_0000115 @default.
- Bd60b39f97feef479dee1a35a59717c1a annotatedSource NCIT_C28989 @default.
- Bd60b39f97feef479dee1a35a59717c1a annotatedTarget "A topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04)" @default.