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- Bd664cce0241148a1b35f4f5fe741a7e0 NCIT_P378 "NCI" @default.
- Bd664cce0241148a1b35f4f5fe741a7e0 type Axiom @default.
- Bd664cce0241148a1b35f4f5fe741a7e0 annotatedProperty IAO_0000115 @default.
- Bd664cce0241148a1b35f4f5fe741a7e0 annotatedSource NCIT_C117229 @default.
- Bd664cce0241148a1b35f4f5fe741a7e0 annotatedTarget "An immunoconjugate consisting of anti-carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) conjugated to a cytotoxic agent, with potential antineoplastic activity. Upon administration of tusamitamab ravtansine the antibody moiety targets CEACAM5 on tumor cells. Upon antibody/antigen binding and internalization, the immunoconjugate releases the cytotoxic agent, which results in tumor cell death. CEACAM5, a member of the CEA family of proteins that plays a key role in cell migration, cell invasion, and cell adhesion, is overexpressed by a variety of cancer cell types." @default.