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- Bd80b70a4c2067d9f19c3b8d7c06893ec NCIT_P378 "NCI" @default.
- Bd80b70a4c2067d9f19c3b8d7c06893ec type Axiom @default.
- Bd80b70a4c2067d9f19c3b8d7c06893ec annotatedProperty IAO_0000115 @default.
- Bd80b70a4c2067d9f19c3b8d7c06893ec annotatedSource NCIT_C29503 @default.
- Bd80b70a4c2067d9f19c3b8d7c06893ec annotatedTarget "An arylalkanoic acid and non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory and antipyretic activities. Although the exact mechanism through which tolmetin exerts its effects has yet to be fully elucidated, this agent appears to inhibit the enzyme prostaglandin synthase. This prevents the formation of prostaglandins from prostaglandin precursors, including the synthesis of the inflammatory prostaglandin E2 (PGE2) from the precursor prostaglandin H2 (PGH2). This prevents prostaglandin-mediated effects, including pain, inflammation and fever." @default.