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- Bd81b617936289a0da692f5f95c3c1afe NCIT_P378 "NCI" @default.
- Bd81b617936289a0da692f5f95c3c1afe type Axiom @default.
- Bd81b617936289a0da692f5f95c3c1afe annotatedProperty IAO_0000115 @default.
- Bd81b617936289a0da692f5f95c3c1afe annotatedSource NCIT_C2635 @default.
- Bd81b617936289a0da692f5f95c3c1afe annotatedTarget "An orally active synthetic antifibrotic agent structurally similar to pyridine 2,4-dicarboxylate. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis. (NCI04)" @default.