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- Bd92aae6c4b4b078baff17859d8523046 NCIT_P378 "NCI" @default.
- Bd92aae6c4b4b078baff17859d8523046 type Axiom @default.
- Bd92aae6c4b4b078baff17859d8523046 annotatedProperty IAO_0000115 @default.
- Bd92aae6c4b4b078baff17859d8523046 annotatedSource NCIT_C183523 @default.
- Bd92aae6c4b4b078baff17859d8523046 annotatedTarget "A preparation of off-the-shelf natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) specific for the cluster of differentiation 33 (CD33) antigen, with potential immunostimulating and antineoplastic activities. Upon administration, the allogeneic anti-CD33 CAR NK cells target and bind to CD33 expressed on the surface of tumor cells. This induces selective toxicity in tumor cells expressing CD33. CD33 is expressed on normal non-pluripotent hematopoietic stem cells and on myeloid leukemia cells." @default.