Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bd9bf71ffefa51695ef92ebafa76cdc7c> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bd9bf71ffefa51695ef92ebafa76cdc7c NCIT_P378 "NCI" @default.
- Bd9bf71ffefa51695ef92ebafa76cdc7c type Axiom @default.
- Bd9bf71ffefa51695ef92ebafa76cdc7c annotatedProperty IAO_0000115 @default.
- Bd9bf71ffefa51695ef92ebafa76cdc7c annotatedSource NCIT_C61103 @default.
- Bd9bf71ffefa51695ef92ebafa76cdc7c annotatedTarget "The orally available hydrochloride salt of the opioid agonist noscapine, a phthalideisoquinoline alkaloid derived from the opium poppy Papaver somniferum, with mild analgesic, antitussive, and potential antineoplastic activities. Noscapine binds to tubulin and alters its conformation, resulting in a disruption of the dynamics of microtubule assembly (by increasing the time that microtubules spend idle in a paused state) and subsequently, the inhibition of mitosis and tumor cell death. Unlike other tubulin inhibitors such as the taxanes and vinca alkaloids, noscapine does not affect microtubule polymerization." @default.