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- Bdd609add5c02374adcce9cc9d179e379 NCIT_P378 "NCI" @default.
- Bdd609add5c02374adcce9cc9d179e379 type Axiom @default.
- Bdd609add5c02374adcce9cc9d179e379 annotatedProperty IAO_0000115 @default.
- Bdd609add5c02374adcce9cc9d179e379 annotatedSource NCIT_C2005 @default.
- Bdd609add5c02374adcce9cc9d179e379 annotatedTarget "A humanized monoclonal antibody targeting the CD40 antigen with potential antineoplastic activity. CD-40, an integral membrane protein found on the surface of B lymphocytes and member of the tumor necrosis factor receptor super-family, is highly overexpressed on the cell surface of a number of B-cell malignancies. Monoclonal antibody SGN-14 specifically binds to and inhibits CD-40, thereby inhibiting cell proliferation and inducing cell lysis via antibody-dependent cellular cytotoxicity (ADCC) in cells." @default.