Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bddd4cec632bf81f716c38e81a0482d30> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bddd4cec632bf81f716c38e81a0482d30 NCIT_P378 "NCI" @default.
- Bddd4cec632bf81f716c38e81a0482d30 type Axiom @default.
- Bddd4cec632bf81f716c38e81a0482d30 annotatedProperty IAO_0000115 @default.
- Bddd4cec632bf81f716c38e81a0482d30 annotatedSource NCIT_C66935 @default.
- Bddd4cec632bf81f716c38e81a0482d30 annotatedTarget "A second-generation antisense oligonucleotide against survivin mRNA with potential antitumor activity. Gataparsen hybridizes to survivin mRNA, thereby blocking translation of survivin protein, a member of the inhibitor of apoptosis (IAP) family. Survivin, expressed during embryonal development, is upregulated in a variety of human cancers while absent in most normal adult cells; its expression in tumors is associated with a more aggressive phenotype, shorter survival times, and a decreased response to chemotherapy. Silencing expression of survivin potentially leads to restoration of the apoptotic process in cancer cells, thereby facilitating chemotherapeutic treatments." @default.