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- Bdec47132353e744a7957781f80f70caa NCIT_P378 "NCI" @default.
- Bdec47132353e744a7957781f80f70caa type Axiom @default.
- Bdec47132353e744a7957781f80f70caa annotatedProperty IAO_0000115 @default.
- Bdec47132353e744a7957781f80f70caa annotatedSource NCIT_C66599 @default.
- Bdec47132353e744a7957781f80f70caa annotatedTarget "The sodium salt form of thiopental, an ultrashort-acting barbituric acid derivative, with anesthetic activity. Thiopental binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability and induction of anesthesia. In addition, this agent decreases glutamate (Glu) responses." @default.