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- Be0196dd263327b393f43a8b5b2d00321 NCIT_P378 "NCI" @default.
- Be0196dd263327b393f43a8b5b2d00321 type Axiom @default.
- Be0196dd263327b393f43a8b5b2d00321 annotatedProperty IAO_0000115 @default.
- Be0196dd263327b393f43a8b5b2d00321 annotatedSource NCIT_C1804 @default.
- Be0196dd263327b393f43a8b5b2d00321 annotatedTarget "A quinazoline folate analogue with antineoplastic activity. After transport into cells via the reduced folate carrier, raltitrexed undergoes intracellular polyglutamation and blocks the folate-binding site of thymidylate synthase, thereby inhibiting tetrahydrofolate activity and DNA replication and repair and resulting in cytotoxicity. (NCI04)" @default.