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- Be16633d0ede22d22c02daaf84200f5ef NCIT_P378 "NCI" @default.
- Be16633d0ede22d22c02daaf84200f5ef type Axiom @default.
- Be16633d0ede22d22c02daaf84200f5ef annotatedProperty IAO_0000115 @default.
- Be16633d0ede22d22c02daaf84200f5ef annotatedSource NCIT_C142444 @default.
- Be16633d0ede22d22c02daaf84200f5ef annotatedTarget "The act of concluding participation by an enrolled subject prior to completion of all protocol-required elements in a trial. NOTE: Four categories of discontinuation are distinguished: a) dropout: Active discontinuation by a subject (also a noun referring to such a discontinued subject); b) investigator initiated discontinuation (e.g., for cause); c) loss to follow-up: cessation of participation without notice or action by the subject; d) sponsor initiated discontinuation. Note that subject discontinuation does not necessarily imply exclusion of subject data from analysis. "Termination of subject" has a history of synonymous use, but is now considered nonstandard. [After ICH E3, section 10.1 and FDA Guidance for Industry: Submission of Abbreviated Reports & Synopses in Support of Marketing Applications, IV A]" @default.