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- Be2eb534253043f59db250a12cb0a0967 NCIT_P378 "NCI" @default.
- Be2eb534253043f59db250a12cb0a0967 type Axiom @default.
- Be2eb534253043f59db250a12cb0a0967 annotatedProperty IAO_0000115 @default.
- Be2eb534253043f59db250a12cb0a0967 annotatedSource NCIT_C563 @default.
- Be2eb534253043f59db250a12cb0a0967 annotatedTarget "An iodinated analogue of deoxyuridine, with antiviral activity against herpes simplex virus (HSV) and potential radiosensitizing activities. Upon ocular administration, idoxuridine (IUdR) is converted to its mono-, di-, and triphosphate forms, is incorporated into DNA and disrupts viral replication. Upon oral administration of the idoxuridine prodrug ropidoxuridine and hepatic conversion by aldehyde oxidase into idoxuridine, this agent incorporates into DNA and sensitizes cells to ionizing radiation by increasing DNA strand breaks." @default.