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- Be3e94ca3600fc80a02997832a96c0c7e NCIT_P378 "NCI" @default.
- Be3e94ca3600fc80a02997832a96c0c7e type Axiom @default.
- Be3e94ca3600fc80a02997832a96c0c7e annotatedProperty IAO_0000115 @default.
- Be3e94ca3600fc80a02997832a96c0c7e annotatedSource NCIT_C172802 @default.
- Be3e94ca3600fc80a02997832a96c0c7e annotatedTarget "A population of closely human leukocyte antigen (HLA)-matched, off-the-shelf (OTS), donor-derived cytotoxic T lymphocytes (CTLs) that are specifically reactive towards six viruses, Epstein-Barr virus (EBV), cytomegalovirus (CMV), adenovirus (AdV), human herpesvirus 6 (HHV6; HHV-6), human polyomavirus type I (BKV) and human polyomavirus type II (JC virus; JCV), with potential antiviral activity. Upon infusion into allogeneic hematopoietic stem cell transplant (HSCT) recipients and immunocompromised patients, posoleucel provides virus-specific cellular immunity and causes specific anti-viral effects against active viral infections. This may prevent EBV, CMV, AdV, HHV6, BKV and JCV reactivation and infection, and inhibits viral-associated diseases." @default.