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- Be404f15348e60b76ddfc9aefadea982d NCIT_P378 "NCI" @default.
- Be404f15348e60b76ddfc9aefadea982d type Axiom @default.
- Be404f15348e60b76ddfc9aefadea982d annotatedProperty IAO_0000115 @default.
- Be404f15348e60b76ddfc9aefadea982d annotatedSource NCIT_C102853 @default.
- Be404f15348e60b76ddfc9aefadea982d annotatedTarget "A monoclonal antibody directed against transforming growth factor-beta receptor type II (TGF-beta RII) with potential antineoplastic activity. Anti-TGF-beta RII monoclonal antibody IMC-TR1 specifically targets and binds to TGF-beta R11, thereby preventing the activation of TGF-beta RII-mediated signaling pathways. TGF-beta RII is mutated in a number of cancer cell types and is involved in cancer cell proliferation and tumor progression." @default.