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- Be4608068b0bdc839e7634be8e3eee2ce NCIT_P378 "NCI" @default.
- Be4608068b0bdc839e7634be8e3eee2ce type Axiom @default.
- Be4608068b0bdc839e7634be8e3eee2ce annotatedProperty IAO_0000115 @default.
- Be4608068b0bdc839e7634be8e3eee2ce annotatedSource NCIT_C804 @default.
- Be4608068b0bdc839e7634be8e3eee2ce annotatedTarget "A group of agents that includes retinol (Vitamin A) and related compounds with potential antineoplastic and/or chemopreventive activities. A retinoic acid agent binds to and/or activates specific nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs), thereby modulating transcription of genes responsible for cell differentiation and proliferation. A retinoic acid agent may exhibit immunomodulatory and anti-inflammatory properties and may inhibit ornithine decarboxylase, resulting in a decrease in polyamine synthesis and keratinization. (NCI04)" @default.