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- Be62ab3ab30ae34c3646abe65e9fde18c NCIT_P378 "NCI" @default.
- Be62ab3ab30ae34c3646abe65e9fde18c type Axiom @default.
- Be62ab3ab30ae34c3646abe65e9fde18c annotatedProperty IAO_0000115 @default.
- Be62ab3ab30ae34c3646abe65e9fde18c annotatedSource NCIT_C26191 @default.
- Be62ab3ab30ae34c3646abe65e9fde18c annotatedTarget "Heterotrimeric G Protein Subunit Genes encode Heterotrimeric G Protein signal transducers, attached to the plasma membrane, that connect seven transmembrane cell surface G-protein coupled receptors to intracellular signal transduction effectors and pathways. Inactive G proteins consist of alpha/beta/gamma complexes that signal as dissociated GTP-bound alpha subunit or the beta/gamma complex. GTP hydrolysis by the inherent GTPase reverts the alpha subunit to its inactive (heterotrimeric) form. Receptors coupled to G proteins communicate signals from hormones, neurotransmitters, chemokines, and autocrine and paracrine factors. (NCI)" @default.