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- Be66ca05d33675364044830e1fd3daa23 NCIT_P378 "NCI" @default.
- Be66ca05d33675364044830e1fd3daa23 type Axiom @default.
- Be66ca05d33675364044830e1fd3daa23 annotatedProperty IAO_0000115 @default.
- Be66ca05d33675364044830e1fd3daa23 annotatedSource NCIT_C65329 @default.
- Be66ca05d33675364044830e1fd3daa23 annotatedTarget "The sodium salt form of cilastatin, a renal dehydropeptidase inhibitor, that can be used to inhibit the activity of renal dehydropeptidase. Upon administration of cilastatin sodium, cilastatin targets, binds to and inhibits the activity of renal dehydropeptidase. This reduces the breakdown of drugs, such as the broad spectrum beta-lactam carbapenem imipenem, by renal dehydropeptidase, and thereby increases the activity and therapeutic effect of such drugs that would otherwise be metabolized by renal dehydropeptidase." @default.