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- Be692b8f91b90f72a22d34635ef4e5a50 NCIT_P378 "NCI" @default.
- Be692b8f91b90f72a22d34635ef4e5a50 type Axiom @default.
- Be692b8f91b90f72a22d34635ef4e5a50 annotatedProperty IAO_0000115 @default.
- Be692b8f91b90f72a22d34635ef4e5a50 annotatedSource NCIT_C47425 @default.
- Be692b8f91b90f72a22d34635ef4e5a50 annotatedTarget "A barbiturate that exerts its effect by mimicking the inhibitory effect of gamma-aminobutyric acid (GABA) by binding to a site, distinct from the benzodiazepine binding site, on the GABA receptor. This leads to an increase in the duration of GABA-mediated opening of chloride channels and enhances the inhibitory effect of GABA. Consequently, its physiologic effects include sedation, hypnosis, reduction of anxiety, and respiratory depression and the drug causes tolerance and dependence." @default.