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- Beabaaa6c342fefadc8f258330144bb38 hasDbXref "PMID:23616747" @default.
- Beabaaa6c342fefadc8f258330144bb38 type Axiom @default.
- Beabaaa6c342fefadc8f258330144bb38 annotatedProperty comment @default.
- Beabaaa6c342fefadc8f258330144bb38 annotatedSource CL_0000129 @default.
- Beabaaa6c342fefadc8f258330144bb38 annotatedTarget "Unlike macroglial cells, microglial cells arise from hematopoietic stem cells in the yolk sac during early embryogenesis that populate the central nervous system. They derive from embryonic mesoderm and are not from neuroectoderm where glioblast develops from. Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive." @default.