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- Beafa6132b4ff0d0edde87f294e9cec8d NCIT_P378 "NCI" @default.
- Beafa6132b4ff0d0edde87f294e9cec8d type Axiom @default.
- Beafa6132b4ff0d0edde87f294e9cec8d annotatedProperty IAO_0000115 @default.
- Beafa6132b4ff0d0edde87f294e9cec8d annotatedSource NCIT_C173964 @default.
- Beafa6132b4ff0d0edde87f294e9cec8d annotatedTarget "An orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR), with potential antineoplastic activity. Upon oral administration, FGFR inhibitor CPL304110 binds to and inhibits FGFR, which results in the inhibition of FGFR-mediated signal transduction pathways. This inhibits proliferation in FGFR-overexpressing tumor cells. FGFR, a family of receptor tyrosine kinases upregulated in many tumor cell types, plays a key role in cellular proliferation and survival." @default.