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- Bec3b615f665208628d2a9a9fa59ad624 NCIT_P378 "NCI" @default.
- Bec3b615f665208628d2a9a9fa59ad624 type Axiom @default.
- Bec3b615f665208628d2a9a9fa59ad624 annotatedProperty IAO_0000115 @default.
- Bec3b615f665208628d2a9a9fa59ad624 annotatedSource NCIT_C677 @default.
- Bec3b615f665208628d2a9a9fa59ad624 annotatedTarget "A triphenylethylene nonsteroidal agent that acts as a partial estrogen antagonist. Nafoxidine competes with endogenous estrogen for binding to specific estrogen receptors. This agent also inhibits angiogenesis in some tissues by blocking the effects of fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF); paradoxically, it may enhance angiogenesis in uterine tissue. Nafoxidine also induces oxidative stress, protein kinase C and calcium signaling. (NCI04)" @default.