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- Bec3e1ffdb21bc5d5974dd0d0f5aa15ec NCIT_P378 "NCI" @default.
- Bec3e1ffdb21bc5d5974dd0d0f5aa15ec type Axiom @default.
- Bec3e1ffdb21bc5d5974dd0d0f5aa15ec annotatedProperty IAO_0000115 @default.
- Bec3e1ffdb21bc5d5974dd0d0f5aa15ec annotatedSource NCIT_C1574 @default.
- Bec3e1ffdb21bc5d5974dd0d0f5aa15ec annotatedTarget "An orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities. Alitretinoin binds to and activates nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR); these activated receptors act as transcription factors, regulating gene expression that results in the inhibition of cell proliferation, induction of cell differentiation, and apoptosis of both normal cells and tumor cells." @default.