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- Bec7b95f9028c3d673f258cde80dda39f NCIT_P378 "NCI" @default.
- Bec7b95f9028c3d673f258cde80dda39f type Axiom @default.
- Bec7b95f9028c3d673f258cde80dda39f annotatedProperty IAO_0000115 @default.
- Bec7b95f9028c3d673f258cde80dda39f annotatedSource NCIT_C83891 @default.
- Bec7b95f9028c3d673f258cde80dda39f annotatedTarget "A small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein. Inhibition of MTP by lomitapide blocks transfer of lipid to apo-B, and as a result emerging apo-B is destroyed and lipoprotein secretion is inhibited." @default.