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- Becc573d1b2ada682e30e51eb567b57dd NCIT_P378 "NCI" @default.
- Becc573d1b2ada682e30e51eb567b57dd type Axiom @default.
- Becc573d1b2ada682e30e51eb567b57dd annotatedProperty IAO_0000115 @default.
- Becc573d1b2ada682e30e51eb567b57dd annotatedSource NCIT_C47597 @default.
- Becc573d1b2ada682e30e51eb567b57dd annotatedTarget "The sodium salt form of meclofenamate, an anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Meclofenamate sodium inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of meclofenamate sodium. Meclofenamate sodium also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation." @default.