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- Bed1961200521701b1d5cffe4718d78e1 NCIT_P378 "NCI" @default.
- Bed1961200521701b1d5cffe4718d78e1 type Axiom @default.
- Bed1961200521701b1d5cffe4718d78e1 annotatedProperty IAO_0000115 @default.
- Bed1961200521701b1d5cffe4718d78e1 annotatedSource NCIT_C1835 @default.
- Bed1961200521701b1d5cffe4718d78e1 annotatedTarget "The sodium salt form of batabulin, a synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. Batabulin covalently binds to and selectively modifies the beta 1, beta 2, beta 3, and beta 4 isotypes of beta tubulin at a conserved cysteine residue, resulting in disruption of microtubule polymerization, collapse of the cytoskeleton, an increase in chromosomal ploidy, cell cycle arrest, and tumor cell apoptosis." @default.