Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bed2b0fa7b6bf83da62339e80710e1db1> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bed2b0fa7b6bf83da62339e80710e1db1 NCIT_P378 "BIOCARTA" @default.
- Bed2b0fa7b6bf83da62339e80710e1db1 type Axiom @default.
- Bed2b0fa7b6bf83da62339e80710e1db1 annotatedProperty NCIT_P325 @default.
- Bed2b0fa7b6bf83da62339e80710e1db1 annotatedSource NCIT_C39215 @default.
- Bed2b0fa7b6bf83da62339e80710e1db1 annotatedTarget "Once retinoids are bound by the RAR/RXR heterodimer they became transcriptional activated. As a consequence they are degraded by the proteasome. Phosphorylation in the activation domain one (AF1) and presence of the activation domain 2 (AF2) trigger the ubiquitination of the receptors. Moreover, heterodimerization of RAR and RXR accelerate degradation of the receptors. (This definition may be outdated - see the DesignNote.)" @default.