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- Bed32bca4b63b1730af6b99c379f5c1e5 NCIT_P378 "NCI" @default.
- Bed32bca4b63b1730af6b99c379f5c1e5 type Axiom @default.
- Bed32bca4b63b1730af6b99c379f5c1e5 annotatedProperty IAO_0000115 @default.
- Bed32bca4b63b1730af6b99c379f5c1e5 annotatedSource NCIT_C486 @default.
- Bed32bca4b63b1730af6b99c379f5c1e5 annotatedTarget "A semisynthetic estrogen. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. (NCI04)" @default.