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- Bed8ffe7f3e0830a7a69b6cb9abbdc780 NCIT_P378 "NCI" @default.
- Bed8ffe7f3e0830a7a69b6cb9abbdc780 type Axiom @default.
- Bed8ffe7f3e0830a7a69b6cb9abbdc780 annotatedProperty IAO_0000115 @default.
- Bed8ffe7f3e0830a7a69b6cb9abbdc780 annotatedSource NCIT_C772 @default.
- Bed8ffe7f3e0830a7a69b6cb9abbdc780 annotatedTarget "A benzoic acid derivative with antihyperuricemic property. Probenecid competitively inhibits the active reabsorption of urate at the proximal tubule in the kidney thereby increasing urinary excretion of uric acid and lowering serum urate concentrations. This prevents urate deposition and promotes resolution of existing urate deposits. In addition, probenecid modulates the transport of organic acids and acidic drugs at the proximal and distal renal tubule, thereby increasing the drug serum concentration." @default.