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- Beea8e97294926d2edab8de65faafbbf8 NCIT_P378 "NCI" @default.
- Beea8e97294926d2edab8de65faafbbf8 type Axiom @default.
- Beea8e97294926d2edab8de65faafbbf8 annotatedProperty IAO_0000115 @default.
- Beea8e97294926d2edab8de65faafbbf8 annotatedSource NCIT_C103273 @default.
- Beea8e97294926d2edab8de65faafbbf8 annotatedTarget "An orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, erdafitinib binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival." @default.