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- Beebb47aee7145c097f25b1ad4a9da394 NCIT_P378 "NCI" @default.
- Beebb47aee7145c097f25b1ad4a9da394 type Axiom @default.
- Beebb47aee7145c097f25b1ad4a9da394 annotatedProperty IAO_0000115 @default.
- Beebb47aee7145c097f25b1ad4a9da394 annotatedSource NCIT_C72706 @default.
- Beebb47aee7145c097f25b1ad4a9da394 annotatedTarget "A broad-spectrum, semisynthetic penicillin derivative with antibacterial activity. Aspoxicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis." @default.