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- Bef4350cb0d797eb5ad9fea38752acf9c NCIT_P378 "NCI" @default.
- Bef4350cb0d797eb5ad9fea38752acf9c type Axiom @default.
- Bef4350cb0d797eb5ad9fea38752acf9c annotatedProperty IAO_0000115 @default.
- Bef4350cb0d797eb5ad9fea38752acf9c annotatedSource NCIT_C367 @default.
- Bef4350cb0d797eb5ad9fea38752acf9c annotatedTarget "A phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting." @default.