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- Befcb2290b3383e9f815945d0600b1376 NCIT_P378 "NCI" @default.
- Befcb2290b3383e9f815945d0600b1376 type Axiom @default.
- Befcb2290b3383e9f815945d0600b1376 annotatedProperty IAO_0000115 @default.
- Befcb2290b3383e9f815945d0600b1376 annotatedSource NCIT_C47552 @default.
- Befcb2290b3383e9f815945d0600b1376 annotatedTarget "A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05)" @default.