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- Befe6417a578f7851aaacf61a735d4c7d NCIT_P378 "NCI" @default.
- Befe6417a578f7851aaacf61a735d4c7d type Axiom @default.
- Befe6417a578f7851aaacf61a735d4c7d annotatedProperty IAO_0000115 @default.
- Befe6417a578f7851aaacf61a735d4c7d annotatedSource NCIT_C767 @default.
- Befe6417a578f7851aaacf61a735d4c7d annotatedTarget "A synthetic piperazine derivative and an alpha-1 adrenergic receptor inhibitor used primarily as an anti-hypertensive. Prazosin's effects are most pronounced in the large resistance vessels (i.e. arterioles) and result in a decrease in total systemic vascular resistance (SVR) without a rebound or reflex tachycardia. To a lesser extent, this agent also decreases the tone of the bladder sphincter, thereby allowing the opening of the bladder into the urethra and thus relieving the urinary conditions associated with benign prostatic hypertrophy." @default.