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- Bf011a232acb86be098bf9f50388bd70b NCIT_P378 "NCI" @default.
- Bf011a232acb86be098bf9f50388bd70b type Axiom @default.
- Bf011a232acb86be098bf9f50388bd70b annotatedProperty IAO_0000115 @default.
- Bf011a232acb86be098bf9f50388bd70b annotatedSource NCIT_C65238 @default.
- Bf011a232acb86be098bf9f50388bd70b annotatedTarget "A synthetic catecholamine with positive chronotropic and inotropic properties, used in echocardiography and diagnostic coronary angiography. Arbutamine binds to and activates beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and increasing force of myocardial contraction. By exerting a chronotropic and inotropic effect, arbutamine mimics the cardiac stress caused by exercise that may prevent adequate tissue perfusion and oxygenation, and may provoke myocardial ischemia in patients with coronary artery disease." @default.