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- Bf16dd9835e840180951fdcc888a78e17 NCIT_P378 "NCI" @default.
- Bf16dd9835e840180951fdcc888a78e17 type Axiom @default.
- Bf16dd9835e840180951fdcc888a78e17 annotatedProperty IAO_0000115 @default.
- Bf16dd9835e840180951fdcc888a78e17 annotatedSource NCIT_C2617 @default.
- Bf16dd9835e840180951fdcc888a78e17 annotatedTarget "A synthetic sequence of DNA constructed in the antisense orientation to a sequence of DNA in epidermal growth factor receptor (EGFR), a member of the erbB gene family. EGFR antisense DNA suppresses the expression of EGFR by tumor cells, thereby inhibiting tumor cell proliferation and decreasing tumor growth. This agent also appears to reduce the invasiveness of certain breast cancer cells. Members of the erbB gene family are overexpressed in many cancers and play roles in carcinogenesis and the regulation of cell proliferation. (NCI04)" @default.