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- Bf1ee3257a74ed65c0835c8f11807998c NCIT_P378 "NCI" @default.
- Bf1ee3257a74ed65c0835c8f11807998c type Axiom @default.
- Bf1ee3257a74ed65c0835c8f11807998c annotatedProperty IAO_0000115 @default.
- Bf1ee3257a74ed65c0835c8f11807998c annotatedSource NCIT_C29358 @default.
- Bf1ee3257a74ed65c0835c8f11807998c annotatedTarget "The maleate salt form of pheniramine, an alkylamine derivative with antihistaminic and vasodilatory properties. Pheniramine maleate binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide. Subsequent lack of activation of guanylyl cyclase through nitric oxide results in decreased cyclic GMP (cGMP) levels, thereby inhibiting constriction of smooth muscle tissue, and decreased capillary permeability and histamine-activated allergic reactions." @default.