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- Bf316dda26a7e5435a599744ed5efb8be NCIT_P378 "NCI" @default.
- Bf316dda26a7e5435a599744ed5efb8be type Axiom @default.
- Bf316dda26a7e5435a599744ed5efb8be annotatedProperty IAO_0000115 @default.
- Bf316dda26a7e5435a599744ed5efb8be annotatedSource NCIT_C29619 @default.
- Bf316dda26a7e5435a599744ed5efb8be annotatedTarget "The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair follicles and adrenal glands by 5-alpha reductase. Dihydrotestosterone exerts its action similar to testosterone, which binds to and activates specific nuclear androgen receptors. After translocation into the nucleus, the activated hormone-receptor complex binds to the androgen response elements on the DNA and activates gene expressions that are required for sex development. Dihydrotestosterone is responsible for the formation of male primary sex characteristics and most male secondary sex characteristics during puberty, such as muscular growth, facial and body hair growth, and deepening of the voice." @default.